“A CINV1-glucose-HXK1-EIN3-PAP1/PIP5K9-CINV1 loop contributes to the modulation of CINV1 activity regulating root growth by glucose signaling”
Professor Meng Laisheng and his team of the Key Laboratory of Biotechnology for Medical Plant of Jiangsu Province published an online research paper titled “Arabidopsis CytosolicInvertase Mediated Root Growth Is Feedback-Regulated by A Glucose-Dependent Signaling Loop” in Plant Physiology.
The disaccharide sucrose, key matter toshape plant growth, cannot be utilized directly. In this context, glucose controls the stability of the transcription factor Ethylene-Insensitive3 (EIN3) via the function of Hexokinase1 (HXK1), a glucose sensor. Thus, invertase, especially the major neutral cytosolic invertase (CINV), constitutes a key point of control for plant growth. However, the cognate regulatory mechanisms that modulate CINV activity remain unclear.
Therefore, Prof. Meng and his research teamdemonstrate that in Arabidopsis thaliana EIN3 binds directly to both thepromoters of Production of Anthocyanin Pigment1 (PAP1) and PhosphatidylinositolMonophosphate 5-Kinase 9 (PIP5K9), repressing and enhancing their expression, respectively. And they make the contribution that a CINV1-glucose-HXK1-EIN3-PAP1/PIP5K9-CINV1 loop contributes to the modulation of CINV1 activity regulating root growth by glucose signaling.
This study was supported by general program of National Natural Science Foundation of China and program of Xuzhou agriculture science and technology. Prof. Meng Laisheng and Wei Zhiqin, a postgraduate student of JSNU are co-first authors of this paper. And Prof. Meng is the corresponding author. Jiangsu Normal University is the first author’s affiliation.
Prof. Meng Laisheng was introduced to Jiangsu Normal University in 2016. His research interest is Plant Molecular Biology. Hosting one program of Xuzhou agriculture science and technology, he has published many research papers in Plant Physiol., PBJ, PCE, Genetics, JAFC as first author or corresponding author in recent five years.