Dr. Yao is now professor of School of Chemistry & Materials Science. He has engaged in the study of asymmetric Series Synthesis Promoted by Organic Micromolecule as well as Series Reaction Promoted by Electrochemistry.
Research Interests
Asymmetric Series Synthesis Promoted by Organic Micromolecule
Series Reaction Promoted by Electrochemistry
Educational Background
Visiting Scholar in Organic Chemistry, Davis, University of California, 2012-2013;
Visiting Scholar in Organic Chemistry, Peking University, 2008-2009;
Doctor in Agricultural Pharmacology, Nankai University, 2002-2005;
Master in Organic Chemistry, Soochow University, 1995-1998;
Bachelor in Chemistry Education, XZNU (now JSNU), 1991-1995.
Research Projects in Recent Years
1. Xuzhou Science and Technology Project (No. XJ07065, ¥60,000): The Design, Synthesis and Selection of Fluorescent Materials Based on the System of Naphthalene, Acenaphthene and Phenanthrene. 2007-2008.
2. Xuzhou Science and Technology Project (No. XM09B016, ¥50,000): Study on the Relations of Structure-activity and the Design & Synthesis of Fluorescent Materials. 2009-2011.
3. Jiangsu Institutes of Higher Learning Natural Science Research Key Project (No. 09KJA430003, ¥150,000): Study on the Relations of Structure-activity and the Design & Synthesis of Fluorescent Materials.2009-2012.
4. National Natural Science Fund Special Fund Project (No. 21242014, ¥100,000): New-type Series Reaction of NHC Catalysis and Its Application in Heterocyclic Synthesis. 2013.
5. National Natural Science Fund Special Fund Project (No. 21372101, ¥800,000): The Effective Construction of Ring Skeleton of New-type Series Reaction Based on NHC Catalysis. 2014-2017.
Selected Publications
1. Wang Yuanfeng, Pan Jian, Dong Jingjiao, Yu Chenxia, Li Tuanjie, Wang Xiangshan, Shen Shide, Yao Changsheng*. (2017). N-Heterocyclic Carbene-Catalyzed [4 + 2] Cyclization of Saturated Carboxylic Acid with o-Quinone Methides through in Situ Activation: Enantioselective Synthesis of Dihydrocoumarins. Journal of Organic Chemistry, 82(3), 1790-1795.
2. Sun Baomin, Gao Lijiu, Shen Shide, Yu Chenxia, Li Tuanjie, Xie Yuanwei, Yao Changsheng*. (2017). NHC-catalyzed [4+2] annulation of 2-bromo-2-enals with acylhydrazones: enantioselective synthesis of δ-lactams. Organic & Biomolecular Chemistry, 15(4), 991-997.
3. Xie Yuanwei, Yu Chenxia, Que Yonglei, Li Tuanjie, Wang Yuhong, Lu Yinan, Wang Wenjing, Shen Shide, Yao Changsheng*. (2016). N-Heterocyclic carbene-triggered transition-metal-free synthesis of 2,3-disubstituted benzofuran derivatives. Organic & Biomolecular Chemistry, 14(27), 6463-6469.
4. Que Yonglei, Lu Yinan, Wang Wenjing, Wang Yuhong, Wang Haotian, Yu Chenxia, Li Tuanjie, Wang Xiangshan, Shen Shide, Yao Changsheng*. (2016). An Enantioselective Assembly of Dihydropyranones through an NHC/LiCl-Mediated in situ Activation of α,β-Unsaturated Carboxylic Acids.Chemistry - An Asian Journal, 11(5), 678-681 (Front Cover).
5. Jia Yanyan, Li Tuanjie, Yu Chenxia, Jiang Bo, Yao Changshen*. (2016). A facile one-pot synthesis of 2,3-diarylated benzofurans via relay NHC and palladium catalysis, Organic & Biomolecular Chemistry, 14(6), 1982-1987.
6. Zhu Ling, Yu Chenxia, Li Tuanjie, Wang Yuhong, Lu Yinan, Wang Wenjing, Yao Changsheng*. (2016). N-Heterocyclic carbene-catalyzed [4 + 2] cyclization of α,β-unsaturated carboxylic acids bearing γ-H with isatins: an enantioselective synthesis of spirocyclic oxindole-dihydropyranones. Organic & Biomolecular Chemistry, 14(4), 1485-1491.
7. Que Yonglei, Xie Yuanwei, Li Tuanjie, Yu Chenxia, Tu Shujiang, Yao Changsheng*. (2015). An N-Heterocyclic Carbene-Catalyzed Oxidative γ-Aminoalkylation of Saturated Carboxylic Acids through in Situ Activation Strategy: Access to δ-Lactam. Organic Letters, 17(24), 6234-6237.
8. Xie Yuanwei, Yu Chenxia, Li Tuanjie, Tu Shujiang, Yao Changsheng*. (2015). An NHC-Catalyzed In Situ Activation Strategy to β-Functionalize Saturated Carboxylic Acid: An Enantioselective Formal [3+2] Annulation for Spirocyclic Oxindolo-γ-butyrolactones. Chemistry - A European Journal, 21(14), 5355-5359.
9. Li Tuanjie, Lu Ting, Yu Chenxia, Yao Changsheng*. (2015). An efficient synthesis of [1,3]dioxolo[4,5-g]thieno[3,4-b]quinolin-8(5H)-ones as novel thiazapodophyllotoxin analogues with potential anticancer activity. Bioorganic & Medicinal Chemistry Letters, 25(7), 1417-1419.
10. Que Yonglei, Li Tuanjie, Yu Chenxia, Wang Xiangshan, Yao Changsheng*. (2015). Enantioselective Assembly of Spirocyclic Oxindole-dihydropyranones through NHC-Catalyzed Cascade Reaction of Isatins with N-Hydroxybenzotriazole Esters of α,β-Unsaturated Carboxylic Acid. Journal of Organic Chemistry, 80(6), 3289-3294.
11. Xie Yuanwei, Que Yonglei, Li Tuanjie, Zhu Ling; Yu Chenxia, Yao Changsheng*. (2015). N-heterocyclic carbene-catalyzed [4+2] cyclization of 2-bromo-2-enal with 3-alkylenyloxindoles: efficient assembly of spirocarbocyclic oxindole. Organic & Biomolecular Chemistry, 13(6), 1829-1835.
12. Xiao Zhaoxin, Yu Chenxia, Li Tuanjie, Wang Xiangshan, Yao Changsheng*. (2014). N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirocyclic Oxindole-Dihydropyranones. Organic Letters, 16(14), 3632-3635.
13. Liu Rui, Yu Chenxia, Xiao Zhaoxin, Li Tuanjie, Wang Xiangshan, Xie Yuanwei, Yao Changsheng*. (2014). NHC-catalyzed oxidative γ-addition of α,β-unsaturated aldehydes to isatins: a high-efficiency synthesis of spirocyclic oxindole-dihydropyranones. Organic & Biomolecular Chemistry, 12(12), 1885-1891.
14. Yao Changsheng*, Wang Ying, Li Tuanjie, Yu Chenxia, Li Liang, Wang Chao. (2013). A pseudo multi-component electrochemical synthesis of spiro dihydrofuran derivatives. Tetrahedron, 69(49), 10593-10597.
15. Yao Changsheng*, Jiao Weihui, Xiao Zhaoxin, Xie Yuanwei, Li Tuanjie, Wang Xiangshan, Liu Rui, Yu Chenxia. (2013). A facile synthesis of tetrahydroimidazo[1,2-a]pyridines and tetrahydrobenzoimidazo[1,2,3-ij][1,8]naphthyridines through NHC-catalyzed cascade annulations. RSC Advances, 3(27), 10801-10805.
16. Yao Changsheng, Xiao Zhaoxin, Liu Rui, Li Tuanjie, Jiao Weihui, Yu Chenxia. (2013). N-Heterocyclic-Carbene-Catalyzed Reaction of α-Bromo-α,β-Unsaturated Aldehyde or α,β-Dibromoaldehyde with Isatins: An Efficient Synthesis of Spirocyclic Oxindole-Dihydropyranones. Chemistry - A European Journal, 19(2), 456-459.
17. Yao Changsheng*, Jiao Weihui, Xiao Zhaoxin, Liu Rui, Li Tuanjie, Yu Chenxia. (2013). NHC-catalyzed cascade synthesis of 1-substituted 4-aryl-tetrahydroquinoline-2,5-diones. Tetrahedron, 69(3), 1133-1137.
18. Yao Changsheng*, Qin Bingbin, Zhang Honghong, Lu Jun, Wang Donglin, Tu Shujiang. (2012). One-pot solvent-free synthesis of quinolines by C-H activation/C-C Bond formation catalyzed by recyclable iron(III) triflate. RSC Advances, 2(9), 3759-3764.
19. Yao Changsheng*, Wang Donglin, Lu Jun, Li Tuanjie, Jiao Weihui, Yu Chenxia. (2012). N-Heterocyclic Carbene Catalyzed Reactions of α-Bromo-α,β-unsaturated Aldehydes/α,β-Dibromoaldehydes with 1,3-Dinucleophilic Reagents. Chemistry - A European Journal, 18(7), 1914-1917, S1914/1-S1914/36.
Honors and Awards
Excellent Youth Core Teacher of Jiangsu Institutes of Higher Learning Innovative Project, 2010
Second Prize of Science and Technology Progress, CPCIF, 2008
Contact Information
Email: csyao@jsnu.edu.cn